We’ve got some advance cuts and the synopsis for the upcoming 45th episode of the Spring 2025 anime Kusuriya no Hitorigoto Season 2 Second Cour, titled “Hikibabon”, airing on Friday, June 6th, 2025.
Kusuriya no Hitorigoto is a palace mystery entertainment series based on the novel series by Hinata Natsu, published under Hero Bunko by Imagica Infos and also serialized as manga in Big Gangan and Sunday GX magazines. The series has surpassed a cumulative total of 40 million copies in print. Set in a medieval East Asian-inspired world, it follows Maomao, a young girl who serves as a “poison taster” and solves various challenging cases occurring within the palace.
The second season, which began airing in January 2025, has garnered significant attention, consistently ranking high on various streaming platforms. Furthermore, the first-ever exhibition, “TV Anime Kusuriya no Hitorigoto Exhibition,” started on March 26th, and a collaboration event with Universal Studios Japan is planned for this summer, adding to the excitement around the series.
Episode 45 “Hikibabon” Synopsis
Following Jinmei’s orders, Maomao continues her days focused on creating an elixir for immortality.
One day, Kyouu devises a plan to help Maomao escape, but they are quickly discovered by the guards.
Surei steps in to mediate the commotion, and just as everyone breathes a sigh of relief, Jinmei appears, changing the atmosphere completely. Annoyed by Jinmei’s enjoyment in tormenting Maomao, Kyouu, Surei, and the guards, Maomao unintentionally utters a certain phrase.
Enraged, Jinmei commands that Maomao be taken to the torture chamber.
Kusuriya no Hitorigoto Season 2 Second Cour Episode 45 “Hikibabon” airs from 24:05 JST on Friday, June 6th, 2025, as part of Nihon TV Kei’s “FRIDAY ANIME NIGHT (Fura Ani)” block, broadcasting simultaneously nationwide.
It will also be available on various streaming platforms sequentially after the broadcast ends.
*Broadcast dates and times are subject to change without notice.
Broadcast Information
■Kusuriya no Hitorigoto
Every Friday night from 11:00 PM JST on Nihon TV Kei’s “FRIDAY ANIME NIGHT (Fura Ani)” block, broadcasting simultaneously nationwide!
Also scheduled for sequential distribution on various streaming platforms after the broadcast ends!
※Broadcast dates and times are subject to change without notice.
Staff
| Role | Name |
|---|---|
| Original Work | Hinata Natsu (Hero Bunko／Imagica Infos) |
| Original Character Design | Shino Touko |
| Chief Director／Series Composition | Naganuma Norihiro |
| Director | Fudesaka Akifumi |
| Assistant Director | Nakagawa Kou |
| Script | Kakihara Yuuko |
| Script | Chiba Misuzu |
| Script | Ogawa Hitomi |
| Character Design | Nakaya Yukiko |
| Art Director | Takao Katsumi (ARED) |
| Color Design | Aida Misato |
| CGI Director | Nagai Yuu |
| Cinematography Director | Suzuki Mayo (T2 studio) |
| Editing | Imai Daisuke |
| Sound Director | Hata Shouji (Sound Team Donfan) |
| Music | Kousaki Satoru |
| Music | Kevin Penkin |
| Music | Okehazama Arisa |
| Second Cour Opening Theme | Mrs. GREEN APPLE「Kusushiki」 |
| Second Cour Ending Theme | Omoinotake「Hitorigoto」 |
| Animation Production | TOHO animation STUDIO×OLM |
| Production | 「Kusuriya no Hitorigoto」Production Committee |
Cast
| Character | Voice Actor |
|---|---|
| Maomao | Yuuki Aoi |
| Jinshi | Ootsuka Takeo |
| Gaoshun | Konishi Katsuyuki |
| Gyokuyouhi | Tanezaki Atsumi |
| Rihakahi | Ishikawa Yui |
| Jushihime | Kino Hina |
| Shaolan | Kuno Misaki |
| Shisui | Seto Asami |
| Narration | Shimamoto Sumi |
(C) Hinata Natsu・Imagica Infos／「Kusuriya no Hitorigoto」Production Committee
